Extensive compensatory cis-trans regulation in the evolution of mouse gene expression
نویسندگان
چکیده
منابع مشابه
Extensive compensatory cis-trans regulation in the evolution of mouse gene expression.
Gene expression levels are thought to diverge primarily via regulatory mutations in trans within species, and in cis between species. To test this hypothesis in mammals we used RNA-sequencing to measure gene expression divergence between C57BL/6J and CAST/EiJ mouse strains and allele-specific expression in their F1 progeny. We identified 535 genes with parent-of-origin specific expression patte...
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ژورنال
عنوان ژورنال: Genome Research
سال: 2012
ISSN: 1088-9051
DOI: 10.1101/gr.142281.112